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Ipamorelin vs MK 677: Which SARM is the Muscle’s Favorite?

June 15, 2024 by Edward Smith

If you’re aiming for a sculpted physique but cautious about the risks of certain enhancers like MK 677 and Ipamorelin, you’re not alone. These substances, falling under SARMs and peptides, offer notable muscle and fat loss benefits but come with potential side effects.

Fortunately, there are now safer, natural alternatives designed to mimic these benefits without the health risks. This guide will cover the essentials of MK 677 and Ipamorelin, their drawbacks, and introduce you to natural options that support your fitness goals healthily. Ideal for both seasoned bodybuilders and newcomers, we’ll show you how to pursue your dream physique safely.

Ipamorelin vs MK-677 Review

The Harsh Reality Behind the Gains

Bodybuilding is good; it keeps you fit and healthy, you get stronger and have more stamina, and your body becomes a lot easier on the eyes. However, the struggle to get a better-looking body is real; gruesome, in fact. You have to put in several punishing hours a day, control your eating habits, quit alcohol and smoking, and, in some cases, even forgo the occasional candy. Which is probably why many resort to performance enhancers.

Most performance enhancers were not created to be that. They usually were developed with some medical benefit in sight like a remedy to muscle-wasting diseases or a cure for osteoporosis, obesity, or growth disorders in children. However, these medical marvels have uses elsewhere. A possible medicine for muscle-wasting would mean enhancing the body’s natural capacity for muscle growth, preserving muscle mass, and ensuring quality muscle building. An obesity remedy would ensure improving muscle-to-fat ratio, arresting fat gain, increasing stored fat loss, and so on – you get the idea. These results are very similar to what one would expect from a bodybuilding regimen, too. Hence, the crossover.

If you have been to a gym with bulking in mind, you are aware of the struggles already, so no one would judge your desire to up the gains for less pain. But the truth of the matter is that using performance enhancers is a bad idea on so many levels. Here are a few instances:

  • You cannot professionally compete if you take them.
  • Using such drugs for anabolic gain is unsafe and riddled with side effects, some of which may alter your health permanently.
  • Also, most are difficult to get your hands on so you would have to buy them on the black market, pay obscene amounts of money, and, even then, have no guarantee that you have the real and pure thing.
  • There are additional issues like dosages, cycles, stacks, and PCT to deal with.

Some think that the risks are worth it, but that is not true always though.

After the advent of steroids, SARMs, peptides, and synthetic compounds took over because they were marginally safer. Most SARMs are still in the research phase but have not even reached human trials. So, taking them for aesthetic reasons is plain dangerous.

But bodybuilders and athletes swear by them and often hawk them to newbies because the instantaneous results are awesome. Regardless of whether you use a SARM or hormone, you are risking your health and reputation for bigger arms. Not convinced yet?

Let us compare a SARM, say, Ibutamoren MK 677, and a hormone peptide Ipamorelin. Better yet, we may even change your mind when it comes to using dangerous performance enhancers altogether.

SARM – Ibutamoren MK 677 vs Growth Hormone Releasing Peptides – Ipamorelin

This article aims to apprise you of the various facets of Ibutamoren and Ipamorelin. While both MK 677 and Ipamorelin have gained popularity, their use presents potential health risks and is thus not condoned or recommended by us.

Before we begin, let us take a quick look at the body’s relationship with Human Growth Hormone (HGH). HGH, or somatotropin, is produced and released by the pituitary gland. Its basic goal is to influence various parts of the body, which promotes growth in children. Once the epiphyses in the bones have fused, the role of HGH changes from a primary growth enhancer to maintaining body structure, metabolism, and blood sugar.

There is an elaborate endocrinological system in place that regulates HGH, which is released in short bursts throughout the day, and IGF-1, produced in the liver, is a major player. The better the levels of HGH in the body, the better maintained it is. Healthy young adults with sufficient amounts of the hormone coursing through the blood would also see better bone strength, muscle strength and recovery, increased protein synthesis, and even better sleep quality. However, the body’s human growth hormone secretion lessens with age.

As HGH levels diminish, it begins to show with a sluggish metabolism, fat accumulation, high sugar levels, and declining bone mineral density. As HGH levels continue to decline, these symptoms become pronounced and hard to correct. This is not exactly considered a growth hormone deficiency but the continuing march of time. To counter this debilitating phenomenon and growth hormone deficiencies in children, medical science has been constantly trying to find lasting remedies. Hence, the following.

Ibutamoren MK-677 Review

Ibutamoren MK 677 was developed in 1995 by Merck & Co. and was seen as an alternative remedy for fibromyalgia, osteoporosis in menopausal women, Alzheimer’s disease, and hormonal imbalances. The compound became an instant favorite for several reasons.

Firstly, it was able to increase HGH levels without the usual suspect side effects, including testosterone suppression. Also, Ibutamoren did not interfere with the natural HGH cycle of the body. Because growth hormone could illicit anabolic reactions from the body, athletes began to turn to Ibutamoren to increase HGH levels without injecting synthetic HGH or Somatropin into their bodies (which did have some rather nasty side effects).

Technically speaking, Ibutamoren MK 677 is not a SARM at all but is grouped with others to make life easier. It is a growth hormone secretagogue and ghrelin receptor agonist. The drug is designed to mimic ghrelin or the hunger hormone, which, in turn, influences IGF-1 or insulin-like growth factor. In a very biological process, the activation of IGF-1 increases the body’s ability to gain muscle, enhances muscle recovery and repair, and even attacks stored fat mass.

The compound can even arrest protein catabolism or muscle-wasting, which comes in handy when you are on a calorie-deficit diet, and your body is looking to burn something for energy. Because it is a growth hormone secretagogue, Ibutamoren ups the secretion of HGH, and you already know what that does. Most bodybuilders stick to a 12-week cycle of the compound, and doses vary from 10mg to 25mg, depending on goals.

Ibutamoren has a half-life of 24 hours, but it sets to work almost immediately and wanes just as quickly, too. Users split a day’s dose into two to keep the drug active throughout the workday. On its own, Ibutamoren does not need PCT, but when stacked with other SARMs like RAD 140 or S23, PCT is a must. The drug is versatile and can be used for bulking, cutting, or recomposition cycles simply by adjusting the dosage.

Growth Hormone-Releasing Peptides are non-natural synthetic peptides that have the capacity to attach to growth hormone secretagogue receptors which then increase growth hormone levels in human and animal physiologies. The use of these peptides came into being when steroids and synthetic hormones failed to provide a safe and long-term remedy to deficiency cases in patients. While synthetic HGH would often include daily injections to mimic the real deal, peptides are designed to target the system that HGH naturally would. Several such peptides have been in circulation, one of which is Ipamorelin.

Ipamorelin Review

Ipamorelin, so far, is the latest peptide to make waves in the growth factor family, and it is also considered to be the safest. It is a selective growth hormone (GH) Secretagogue and Ghrelin receptor agonist. Designed to increase human growth hormone levels but without the subsequent appetite stimulation or the increase in cortisol, prolactin, acetylcholine, and aldosterone, Ipamorelin is considered to be the best possible peptide to hit human pituitary glands. Even though it does stimulate the pituitary, Ipamorelin does not increase ghrelin levels, which translates to less appetite stimulation, and neither does it increase cortisol levels. Common side effects of other forms of HGH therapy were cold sweats, jitters, restlessness, and nervousness, which directly resulted from elevated cortisol. This works for athletes, too.

Because of its ability to maintain youthful HGH levels, Ipamorelin quickly made its rounds in gym locker rooms. Here is the catch, though: Ipamorelin cannot do a lot on its own. It usually needs a synthetic GHRH, as well. When used on its own, Ipamorelin has a very nominal effect, but when combined with a GHRH, the results are phenomenal, like significantly faster muscle growth, exponential fat loss, quick recovery, and improved bone density.

Because it is an active medical compound, the dosages are very dicey when it comes to anabolic use. Most users swear that a combination of 100mcg of a GHRH and 100mcg of Ipamorelin can produce exceptional results. Post-cycle therapy is not required with Ipamorelin, but side effects are a reality, which we will cover in the section below.

Benefits & Side Effects

So far, you have only been privy to the good news. As is with all things, bad news is not far behind. Considering that Ibutamoren MK 677 and Ipamorelin were designed for medical use, their recommended dosages were small. For anabolic gains, dosages are extreme, and there would be consequences of use.

Ibutamoren MK 677Ipamorelin
BenefitsSide EffectsBenefitsSide Effects
  • Improves rate of protein synthesis for better muscle-building
  • Arrests muscle wastage
  • Can increase bone mineral density
  • Shortens muscle recovery
  • Improves sleep quality
  • Can improve cognitive function.
  • Significant increase in appetite
  • Joint pains & muscle aches
  • Boosts insulin insensitivity
  • Induces lethargy & fatigue
  • Impacts the pituitary gland
  • Prolactin levels soar.
  • Decreases body fat storage
  • Boosts collagen & protein synthesis
  • Quality muscle tissue
  • Better sleep
  • Increases IGF-1
  • Improves bone density
  • Curbs appetite
  • Curbs prolactin, cortisol & aldosterone.
  • Reduces insulin sensitivity
  • Water retention
  • Carpel tunnel syndrome
  • Headaches.

You must understand that the side effects mentioned above do not appear in any scientific journals. Since neither Ibutamoren nor Ipamorelin are designed to be used for fitness goals, the above lists are drawn from the experiences of users. Your body’s reaction to these compounds could be similar or worse.

Which Is Better for Bodybuilding – Ibutamoren MK 677 or Ipamorelin?

To be honest, using either is a bad idea. They are not meant or designed as fitness aids, and using them pose a constant health risk. That being said, if you had to choose one, Ibutamoren would be the better bad idea.

Ipamorelin is no more in medical use as the FDA claims that it “poses notable safety concerns.” What these concerns really are is not entirely clear. There were some instances of death when Ipamorelin was given to a patient through an IV.  Since then, there was a definite shift in the medical community where researchers were looking for a safer way to boost HGH levels. Similarly, Ibutamoren is just as capable of getting more human growth hormone to run through your veins even though it isn’t an FDA-approved drug yet.

Ipamorelin and other peptides are facing some negative backlash even though they were once touted to be the ‘latest and greatest peptides’ to grace medical history; Ibutamoren still has a good reputation, of sorts. Although, this does not mean that the latter does not have any consequences of use; there are and we have an entire list above. What is being said here is that with Ibutamoren, there is a certain level of control and predictability that the peptides cannot provide. 

If you insist on using dangerous chemicals, Ibutamoren can give you similar effects to Ipamorelin without as much of a risk. The SARM (the term is used very loosely) can give you better skin elasticity, bone mineral content, wound healing, improved recovery, and deep sleep along with the anabolic benefits of bigger stronger muscle mass, more endurance, and fat loss.

Ibutamoren has been through animal studies which show Ibutamoren goes to work almost immediately making it work like a pre-workout supplement. It is also orally active and thus would not require you to inject yourself with synthetic growth hormones. But again, this is just one side of the coin.

The flipside is rather ugly. You have the side effects to deal with. The human bout of trials for the compound has not yet begun, which means that there is no information about the long-term effects of Ibutamoren on human physiology. Because it is a research chemical, you cannot buy it legally from your local drugstore. You would have to resort to less-than-kosher ways to obtain it. Even then, there would be no guarantee that you have the actual compound and just not sugar pills.

In short, it is all one very big risk you would be taking for better quality muscle mass. The odds are not in your favor. But what if there was a safe and effective way to get all the benefits of Ibutamoren, none of the side effects, and still compete professionally? Sounds too good to be true, yes? But such supplements do exist and they really do work.

The Natural, Safe & Legal Alternatives for Ibutamoren MK 677

Natural supplements have a bad reputation resulting from brands making obnoxious claims while delivering very little. However, not every natural supplement brand is like that. Some actually do the work and put together fitness aids that support your fitness goals. Crazy Bulk and Brutal Force are two such companies and have taken the world by storm by creating natural and safe alternatives for anabolic steroids, SARMs, and other hormones.

The goal, for them, was to help eradicate the use of synthetic and dangerous performance enhancers in the fitness world. They have succeeded in creating such supplements, and both feature alternatives for Ibutamoren MK 677.

Crazy Bulk Ibuta 677

CrazyBulk Ibuta 677 Review

This natural Ibutamoren alternative is designed to deliver all the benefits of the SARM minus the side effects or the legal consequences. Using a unique combination of safe, natural, and legal ingredients, Ibuta 677 is the next best thing to the actual Ibutamoren MK 677.

Unlike the research compound, Ibuta 677 naturally augments the activity of the pituitary gland, which releases more HGH into your bloodstream. There is no artificial enhancement here. This, in turn, would increase muscle quality, boost vascularity, speed recovery, and improve your mood.

Of course, this dietary supplement cannot be used for growth hormone deficiency, but the spike in HGH would be enough to boost protein synthesis and muscle repair so that you become a beast in the gym.

Ibuta 677 increases your performance at the gym by enhancing the level at which your body recovers from physical strain. The longer you spend exercising, the greater the testosterone and GH levels course through your veins. The result is bulkier muscles. In addition to that, this fitness aid is equipped to support muscle vascularity, enhance strength and endurance, improve the rate of protein synthesis, and help you maintain focus on your goals.

The only ask is that you take 4 capsules 30 to 45 minutes before training and you are all set. Continue use for at least 2 to 3 months to enjoy the complete range of benefits. There is no fiddling about with dosages, pills, or needles here.

The Ibuta 677 Formula

Of course, the question is how. To understand how Ibuta 677 works, you must take a look at the formula and see what each component brings to the table. The formula includes:

  • Zinc – which is key to protein synthesis and also influences oxygen intake and ATP production in the muscle cells. The protein synthesis supports muscle-building and muscle tissue repair.

  • Vitamin B5 – is primarily responsible for the metabolism of the food you consume. It is additionally responsible for ATP production and the boosting of stamina.

  • L-Arginine HCl – is an amino acid that can help with building muscle tissue, boost energy production, and last but not least, maintain healthy HGH levels.

  • Glycine – helps to activate and stimulate the pituitary gland which helps with the production, release, and maintenance of HGH.

  • L-Glutamine HCl – studies have proven that supplementation of this amino acid can increase HGH up to 78%. This increases the body’s anabolic response and helps you gain more from workout sessions.

  • L-Lysine HCl – is yet another amino acid that focuses its energies on bone strength, bone density, joint health, and collagen synthesis, helping the body recover in significantly less time.

  • L-Ornithine HCl – is a form of the amino acid L-ornithine combined with hydrochloric acid and is added to support protein synthesis, wound healing, and muscle recovery.

  • And L-Tyrosine – is often supplemented to improve cognitive function, maintain mood, and enhance focus. The amino acid also helps to reduce mental exhaustion.
CrazyBulk Ibuta-677 Ingredients

Where to Buy Ibuta 677?

Ready to try Ibuta 677? Visit Crazy Bulk’s website to make your purchase.

  • A single month’s worth (1 bottle) of product would cost $69.99.

However, the more you buy, the more you save.

  • If you purchase two months’ worth of the aid, you get another month’s worth absolutely free – all three bottles for a price of $139.99.

  • For $209.9, you pay for a three-month supply and get a two-month supply free, i.e., for a total of five bottles that will last you five months.

All purchases come with fast and free delivery. All Crazy Bulk products come with a 60-day money-back guarantee. So, if at any point you find that the products are not working for you, you only need to contact customer service for a hassle-free refund process.

Brutal Force IbutaLean

BrutalForce IbutaLean Review

Brutal Force’s IbutaLean is a natural performance enhancer that can rival the effects of the SARM itself. Like its counterpart with Crazy Bulk, IbutaLean also uses natural ingredients to increase the body’s resistance to damage, inflammation, and fatigue. This allows you to spend more fruitful hours at the gym and gives you the capacity to hit the gym the next round with just as much vigor.

With regular IbutaLean use, you would enjoy lean muscle mass growth, significantly faster healing, anti-inflammatory action, and a rise in HGH levels without weight gain from fat. Over time, you would have the bulk and muscle you wished to have.

IbutaLean is formulated to naturally increase HGH levels without negatively affecting corresponding systems in your body. With the surge in HGH, you would be able to enjoy exponential muscle gains, a leaner physique, a natural increase in nitric oxide, better blood circulation, and shorter recovery windows.

You would be expected to take 1 capsule a day, approximately 20 minutes before your first meal of the day. With continuous use of the product over 2 months, at least, you should be on your way to a bigger, stronger, and healthier physique.

The Formula 

IbutaLean works by providing your body with the right nutrients. In addition to L-Arginine (explained above), this fitness supplement uses a combination of herbs like:

  • Maca Root Powder – which is added to maintain optimum hormonal balance, including levels of anabolic hormones like HGH and Testosterone. The herb is also believed to improve the rate of protein synthesis.

  • Hawthorn Berry – is proven to boost the production and release of HGH and also increase nitric oxide levels in the bloodstream. This translates to better nutrient and oxygen supply to the growing muscle tissue.

  • Mucuna Puriens Seed Extract – is a natural testosterone booster and can even help with increasing HGH levels. It also plays a role in the repair and maintenance of muscle tissue, ligaments, and joints, thereby facilitating quick recovery after a punishing day at the gym.
BrutalForce IbutaLean Ingredients

Where to Buy Ibutalean?

Head over to the official Brutal Force website to purchase IbutaLean.

  • A one-month supply of the supplement (1 bottle) is yours for a price of $59.99.
  • If you purchase two bottles at once, you get a third one for free, all 3 bottles for just as little as $119.98.

All purchases warrant free worldwide shipping. Brutal Force also offers a 100-day money-back guarantee. This applies to only bulk purchases, though.

Comparing Ibutamoren MK 677 With the Natural Alternatives

While using the SARM Ibutamoren MK 677 is a bad idea from the get-go, natural supplements are the safer and better choice. Not just because natural supplements are legal but also because Ibuta 677 and IbutaLean have been created to work with the body rather than artificially enhance the natural physiological systems. Instead of forcing your muscle and bone tissue to perform beyond its natural capacity, the legal options repair, enhance, and maintain the anabolic systems so that the results you enjoy are organic and side-effect-free.

Of course, there is one drawback, though (like there is with every good thing). Natural ingredients are affected by a number of factors like age, health, genetics, diet, and lifestyle habits. This means that the results would vary from one individual to the next in both quality and quantity. The results would be there, but unlike the SARM, where you can predict results easily, you cannot do the same with natural supplements. That is barely a drawback but is considered inconvenient at best.

MK-677 Natural Alternatives CrazyBulk Ibuta-677 & BrutalForce IbutaLean

To give you a better understanding, here is a quick recap of all the information we have.

Ibutamoren MK 677Crazy Bulk Ibuta 677Brutal Force IbutaLean
PurposeDeveloped as a possible remedy for fibromyalgia, osteoporosis & Alzheimer’s disease.Formulated as a natural, safe & legal alternative to Ibutamoren MK 677 for anabolic gains.
Pros
  • Quick & uniform results always
  • Results are the same for all users
  • Can be stacked for better results.
  • Uses only safe & natural ingredients
  • Has additional health benefits
  • Legal
  • Has no side effects
  • Easy to use
  • Can be used while professionally competing.
Cons
  • Too many side effects
  • Long-term consequences unknown
  • Illegal for human use
  • Complicated dosage
  • PCT is a must when stacked.
  • Results are affected by external factors
  • Results may vary from one individual to the next.
FDA ApprovalNoNo
WADA ApprovedNoYes
PCT RequiredWhen stacked, yes.No PCT required.
Dosage10 to 25 mg for 12 weeks.4 capsules a day.1 capsule a day.
PriceDepends on the source.$69.99.$59.99.
Refund PolicyRefunds unlikely.60-day money-back guarantee100-day money-back guarantee.
Where to Buy Ibutamoren?Not sold legally.Buy 2 Ibuta 677 from the CrazyBulk Official Website and Get 1 Free Bottle.Buy 2 Ibutalean from the Brutal Force Official Website and Get 1 Free Bottle.

Summary & Verdict

Ibutamoren MK 677 and Ipamorelin are often used to increase athletic performance, muscle building, and weight loss by athletes. Even though, Ibutamoren is the better choice for anabolic gains, the compound is illegal, unsafe, and not approved for human use.

For bodybuilding support, it is recommended that you opt for Crazy Bulk Ibuta 677 or Brutal Force IbutaLean as these supplements are natural, legal, safe, and side-effect-free.

Edward Smith
Edward Smith

Edward Smith, CEO of MK-677 Official and a certified fitness coach, he has been coaching for over five years, working with clients in both personal training sessions and group classes. He specializes in promoting measures that can help promote muscle growth, improved strength, reduced soreness, and improve sleep. Whether you are looking to bulk up or slim down, he has something in favor for you.

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